For research use only. Not for therapeutic Use.
Propionylpromazine-d6 (hydrochloride) is the deuterium labeled Propionylpromazine hydrochloride. Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease[1].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Catalog Number | S000386 |
CAS Number | 1262770-67-1 |
Molecular Formula | C20H19D6ClN2OS |
Purity | ≥95% |
Target | Neuronal Signaling |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Tyers, Mike, et al. Method for treating a brain cancer with ifenprodil. US8058243. |