For research use only. Not for therapeutic Use.
Propyl 4-Hydroxybenzoate (Propyl Paraben) (Cat No.:R012953) is a p-hydroxybenzoate derivative, mainly used as a bactericidal preservative in food, cosmetics and medicine, and also used as a feed preservative.
| Catalog Number | R012953 |
| CAS Number | 94-13-3 |
| Synonyms | 4-Hydroxybenzoic Acid Propyl Ester; 4-Hydroxybenzoic Acid Propyl Ester; Aseptoform P; Bonomold OP; Chemocide PK; Mekkings P; NSC 23515; Propyl Chemosept; Propyl p-Hydroxybenzoate; Propylparasept; n-Propylparaben; |
| Molecular Formula | C10H12O3 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | propyl 4-hydroxybenzoate |
| InChI | InChI=1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3 |
| InChIKey | QELSKZZBTMNZEB-UHFFFAOYSA-N |
| SMILES | CCCOC(=O)C1=CC=C(C=C1)O |
| Reference | </br>1: Lara-Valderrábano L, Rocha L, Galván EJ. Propylparaben reduces the excitability of hippocampal neurons by blocking sodium channels. Neurotoxicology. 2016 Sep 28;57:183-193. doi: 10.1016/j.neuro.2016.09.019. PubMed PMID: 27693446.</br>2: Qadir MA, Ahmed M, Shafiq MI, Ali A, Sadiq A. Analytical Method for the Identification and Assay of Kojic Acid, Methylparaben, and Propylparaben in Cosmetic Products Using UPLC: Application of ISO 12787:2011 Standard. J AOAC Int. 2016 Sep;99(5):1191-6. doi: 10.5740/jaoacint.16-0026. Epub 2016 Jun 21. PubMed PMID: 27329740.</br>3: Szeląg S, Zabłocka A, Trzeciak K, Drozd A, Baranowska-Bosiacka I, Kolasa A, Goschorska M, Chlubek D, Gutowska I. Propylparaben-induced disruption of energy metabolism in human HepG2 cell line leads to increased synthesis of superoxide anions and apoptosis. Toxicol In Vitro. 2016 Mar;31:30-4. doi: 10.1016/j.tiv.2015.11.011. PubMed PMID: 26616278.</br>4: Roy C, Chakrabarty J. Quality by Design-Based Development of a Stability-Indicating RP-HPLC Method for the Simultaneous Determination of Methylparaben, Propylparaben, Diethylamino Hydroxybenzoyl Hexyl Benzoate, and Octinoxate in Topical Pharmaceutical Formulation. Sci Pharm. 2014 Feb 27;82(3):519-39. doi: 10.3797/scipharm.1312-20. eCollection 2014 Sep. PubMed PMID: 25853065; PubMed Central PMCID: PMC4318166. </br> </br> |
