For research use only. Not for therapeutic Use.
Propylthiouracil is a drug used to treat hyperthyroidism by decreasing the amount of thyroid hormone produced by the thyroid gland. Propylthiouracil-d5 is a labelled antihyperthyroid that has been shown to increase the size of adipose tissue in vitro. It is a peroxidase inhibitor.
| Catalog Number | A001221 |
| CAS Number | 51-52-5 |
| Synonyms | NSC 6498, NSC 70461 |
| Molecular Formula | C7H10N2OS |
| Purity | ≥95% |
| Target | Peroxidase Inhibitor |
| Storage | 3 years -20C powder |
| InChIKey | KNAHARQHSZJURB-UHFFFAOYSA-N |
| Reference | </br>1:Propylthiouracil-associated rapidly progressive crescentic glomerulonephritis with double positive anti-glomerular basement membrane and antineutrophil cytoplasmic antibody: the first case report. Kantachuvesiri P, Chalermsanyakorn P, Phakdeekitcharoen B, Lothuvachai T, Niticharoenpong K, Radinahamed P, Turner N, Kantachuvesiri S.CEN Case Rep. 2015 Nov;4(2):180-184. doi: 10.1007/s13730-014-0163-9. Epub 2014 Dec 31. PMID: 28509097 Free PMC Article</br>2:Participants with Normal Weight or with Obesity Show Different Relationships of 6-n-Propylthiouracil (PROP) Taster Status with BMI and Plasma Endocannabinoids. Carta G, Melis M, Pintus S, Pintus P, Piras CA, Muredda L, Demurtas D, Di Marzo V, Banni S, Barbarossa IT.Sci Rep. 2017 May 2;7(1):1361. doi: 10.1038/s41598-017-01562-1. PMID: 28465539 Free PMC Article</br>3:[Pyoderma gangrenosum associated with anti-proteinase 3 antineutrophil cytoplasmic antibodies (PR3-ANCA) induced by propylthiouracil]. Coster A, Dargent JL, de Visscher N, Levecque P, Roquet-Gravy PP.Ann Dermatol Venereol. 2017 May;144(5):368-373. doi: 10.1016/j.annder.2017.01.018. Epub 2017 Mar 11. French. PMID: 28291538 </br>4:Relationship of recovered hepatitis B infection with appearance of toxic propylthiouracil hepatitis. Čalkić L, Bajramović-Omeragić L.Med Glas (Zenica). 2017 Feb 1;14(1):79-84. doi: 10.17392/885-16. PMID: 28165437 Free Article</br>5:Genetic specificity to 6-n-propylthiouracil and its association to dental caries: A Comparative study. Vandal VB, Noorani H, Shivaprakash PK, Walikar B.J Indian Soc Pedod Prev Dent. 2017 Jan-Mar;35(1):83-85. doi: 10.4103/0970-4388.199233. PMID: 28139488 Free Article</br>6:Propylthiouracil-induced liver failure and artificial liver support systems: a case report and review of the literature. Wu DB, Chen EQ, Bai L, Tang H.Ther Clin Risk Manag. 2017 Jan 11;13:65-68. doi: 10.2147/TCRM.S122611. eCollection 2017. PMID: 28138249 Free PMC Article</br>7:First objective evaluation of taste sensitivity to 6-n-propylthiouracil (PROP), a paradigm gustatory stimulus in humans. Sollai G, Melis M, Pani D, Cosseddu P, Usai I, Crnjar R, Bonfiglio A, Tomassini Barbarossa I.Sci Rep. 2017 Jan 11;7:40353. doi: 10.1038/srep40353. PMID: 28074885 Free PMC Article</br>8:Caries risk in children of Udaipur City, India using genetic taste sensitivity to 6-<i>n</i>-propylthiouracil. Karmakar P, Arora R, Patel C, Sarvaiya B, Singh A, Patel M.J Int Soc Prev Community Dent. 2016 Nov-Dec;6(6):523-528. doi: 10.4103/2231-0762.195508. PMID: 28032043 Free PMC Article</br>9:The therapeutic effect of rosuvastatin and propylthiouracil on ameliorating high-cholesterol diet-induced rabbit aortic atherosclerosis and stiffness. Lin PY, Lee FY, Wallace CG, Chen KH, Kao GS, Sung PH, Chua S, Ko SF, Chen YL, Wu SC, Chang HW, Yip HK, Shao PL.Int J Cardiol. 2017 Jan 15;227:938-949. doi: 10.1016/j.ijcard.2016.09.040. Epub 2016 Sep 21. PMID: 27932239 </br>10:Propylthiouracil-Associated Leukocytoclastic Necrotizing Cutaneous Vasculitis: A Case Report and Review of the Literature. Wall AE, Weaver SM, Litt JS, Rae L.J Burn Care Res. 2017 May/Jun;38(3):e678-e685. doi: 10.1097/BCR.0000000000000464. PMID: 27893578 |
