Propylthiouracil-d5

• CAT Number: R008159
• CAS Number: 1189423-94-6
• Molecular Formula: C7H10N2OS
• Molecular Weight: 175.261
• Purity: ≥95%
• Synonyms: 2,3-Dihydro-6-(propyl-d5)-2-thioxo-4(1H)pyrimidinone; 6-(Propyl-d5)-2-thiouracil;?2-Mercapto-4-hydroxy-6-n-propyl-d5-pyrimidine; 2-Mercapto-6-(propyl-d5)-pyrimidin-4-ol; Procasil-d5; Propacil-d5; Propycil-d5
• Storage: 2°C to 8°C
• IUPAC Name: 6-(2,2,3,3,3-pentadeuteriopropyl)-2-sulfanylidene-1H-pyrimidin-4-one
• InChI: InChI=1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)/i1D3,2D2
• InChIKey: KNAHARQHSZJURB-ZBJDZAJPSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])CC1=CC(=O)NC(=S)N1

Propylthiouracil-d5 is a deuterated form of propylthiouracil, a medication used to treat hyperthyroidism by inhibiting the synthesis of thyroid hormones. In this compound, five hydrogen atoms are replaced with deuterium, enhancing its stability and allowing for precise analysis in pharmacokinetic and metabolic studies using techniques such as mass spectrometry. Propylthiouracil-d5 is particularly valuable in research focused on understanding the drug’s absorption, distribution, metabolism, and excretion (ADME) properties.