For research use only. Not for therapeutic Use.
Epoprostenol Sodium is a potent vasodilator and antiplatelet substance with a very short physiologic half-life. The sodium salt is used primarily for the treatment of pulmonary hypertension. Epoprostenol sodium inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.
| Catalog Number | R049578 |
| CAS Number | 61849-14-7 |
| Synonyms | (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-Dihydroxy-prosta-5,13-dien-1-oic Acid Sodium Salt; Epoprostenol Sodium; Flolan; |
| Molecular Formula | C20H31O5 • Na |
| Purity | ≥95% |
| Target | Endogenous Metabolite |
| Solubility | Soluble in DMSO > 10 mM |
| Storage | Desiccate at -80C |
| InChIKey | LMHIPJMTZHDKEW-XQYLJSSYSA-M |
| Reference | </br>1:[Synthesis of D,L-15-methylprostacyclin sodium salt]. Jin BY, Wu YL.Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1987 Oct;9(5):386-9. Chinese. No abstract available. PMID: 2968866 </br>2:Beneficial effects of sodium salt of 17(R)-methyl-20-isopropylidenecarbacyclin on experimentally-induced ischemic hind limb lesions and blood viscosity. Morita A, Kamoshita K, Ito T, Naito Y, Akiyama K, Kobayashi S.Arzneimittelforschung. 1986 Apr;36(4):680-3. PMID: 3521616 </br>3:Antithrombotic effects of sodium salt of 17(R)-methyl-20-isopropylidenecarbacyclin in the arteriole of the hamster cheek pouch. Morita A, Endo K, Mori M, Akiyama K, Kohata K, Kobayashi S.Arzneimittelforschung. 1986 Apr;36(4):676-9. PMID: 3521615 |
