For research use only. Not for therapeutic Use.
Prostaglandin A<sub>1</sub> (PGA<sub>1</sub>) was first isolated as a dehydration product of the PGE<sub>1</sub> compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-<wbr></wbr>inhibitory activity on tumor cells; the IC<sub>50</sub> value for the inhibition of human ovarian cancer is 7.5 µM.
| Catalog Number | R061181 |
| CAS Number | 14152-28-4 |
| Synonyms | 2-(3-Hydroxy-1-octenyl)-5-oxo-3-cyclopentene-1-heptanoic Acid; 15-Hydroxy-9-oxoprosta-10,13-dienoic Acid; 15α-Hydroxy-9-ketoprosta-10,13-dienoic Acid; 15α-Hydroxy-9-oxo-10,13E-prostadienoic Acid; PGA1; Prostaglandin A1; Prostaglandin E1-217 |
| Molecular Formula | C20H32O4 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoic acid |
| InChI | InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12-18,21H,2-11H2,1H3,(H,23,24)/b14-12+/t16-,17-,18+/m0/s1 |
| InChIKey | BGKHCLZFGPIKKU-LDDQNKHRSA-N |
| SMILES | CCCCCC(C=CC1C=CC(=O)C1CCCCCCC(=O)O)O |
