For research use only. Not for therapeutic Use.
Prostaglandin E<sub>1</sub> ethanolamide (PGE<sub>1</sub>-<wbr></wbr>EA) is the ethanolamine-<wbr></wbr>amide analog of PGE<sub>1</sub>. Conversion of AEA, the ethanolamide of arachidonic acid, to PGE<sub>2</sub>-<wbr></wbr>EA has been demonstrated <em>in vitro</em>. It is not established whether this conversion occurs in whole animals, nor has the pharmacology of the resultant prostaglandin ethanolamides been rigorously studied.
| CAS Number | 210976-81-1 |
| Synonyms | Alprostadil Ethanolamide;PGE1-EA |
| Molecular Formula | C22H39NO5 |
| Purity | ≥95% |
| Target | Prostaglandin Receptor |
| Storage | -20°C |
| InChI | InChI=1S/C22H39NO5/c1-2-3-6-9-17(25)12-13-19-18(20(26)16-21(19)27)10-7-4-5-8-11-22(28)23-14-15-24/h12-13,17-19,21,24-25,27H,2-11,14-16H2,1H3,(H,23,28)/b13-12+/t17-,18+,19+,21+/m0/s1 |
| InChIKey | HLQFDRCTTQBTCE-RCDOCOITSA-N |
| SMILES | CCCCCC(O)/C=C/[C@H]1C(O)CC(=O)C1CCCCCCC(=O)NCCO |
| Reference | 1.Yu, M.,Ives, D., and Ramesha, C.S. Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2. The Journal of Biological Chemisty 272, 21181-21186 (1997). |
