For research use only. Not for therapeutic Use.
Prostaglandin E<sub>3</sub> (PGE<sub>3</sub>) is formed <em>via</em> the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. In human ocular tissue, it comprises 2.4% of the COX products formed. When applied to the eyes of a rabbit, a 1 µg dose of PGE<sub>3</sub> decreases intraocular pressure from 21 mmHg to about 17 mmHg.
| Catalog Number | R064944 |
| CAS Number | 802-31-3 |
| Synonyms | PGE3 |
| Molecular Formula | C20H30O5 |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/C20H30O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h3-4,6-7,12-13,15-17,19,21,23H,2,5,8-11,14H2,1H3,(H,24,25)/b6-3-,7-4-,13-12+/t15-,16+,17+,19+/m0/s1 |
| InChIKey | CBOMORHDRONZRN-QLOYDKTKSA-N |
| SMILES | O=C1[C@H](C/C=CCCCC(O)=O)[C@@H](/C=C/[C@@H](O)C/C=CCC)[C@H](O)C1 |
| Reference | 1.Kulkarni, P.S., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in human and rabbit anterior uvea. Prostaglandins 31, 1159-1164 (1986). |
