PROT-IN-1

• CAT Number: I041073
• CAS Number: 329935-45-7
• Molecular Formula: C23H22N2O
• Molecular Weight: 342.43
• Purity: ≥95%
• Synonyms: (4-phenylphenyl)-(4-phenylpiperazin-1-yl)methanone
• InChI: InChI=1S/C23H22N2O/c26-23(21-13-11-20(12-14-21)19-7-3-1-4-8-19)25-17-15-24(16-18-25)22-9-5-2-6-10-22/h1-14H,15-18H2
• InChIKey: VHYSKWYZIZGSJB-UHFFFAOYSA-N
• SMILES: C1CN(CCN1C2=CC=CC=C2)C(=O)C3=CC=C(C=C3)C4=CC=CC=C4

PROT-IN-1 (Compound 2) is a proline transporter (PROT) inhibitor (IC50: 1.48 μM). PROT-IN-1 can be used for research of cognitive disorders[1].

Reference

[1]. Zipp GG, et al. Novel inhibitors of the high-affinity L-proline transporter as potential therapeutic agents for the treatment of cognitive disorders. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3886-90.
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