For research use only. Not for therapeutic Use.
PROT-IN-1（Cat No.:I041073）is a small molecule inhibitor that targets the PROTAC (Proteolysis Targeting Chimera) mechanism, a novel approach for selective protein degradation. By binding to specific E3 ligases and the target protein, PROT-IN-1 facilitates the ubiquitination and subsequent degradation of unwanted proteins, effectively reducing their activity within cells. This targeted protein degradation strategy offers a promising therapeutic approach for diseases driven by overexpressed or malfunctioning proteins, including cancer, neurodegenerative disorders, and immune diseases. PROT-IN-1 is being explored as a potential tool for advancing precision medicine through targeted protein removal.
| CAS Number | 329935-45-7 |
| Synonyms | (4-phenylphenyl)-(4-phenylpiperazin-1-yl)methanone |
| Molecular Formula | C23H22N2O |
| Purity | ≥95% |
| IUPAC Name | (4-phenylphenyl)-(4-phenylpiperazin-1-yl)methanone |
| InChI | InChI=1S/C23H22N2O/c26-23(21-13-11-20(12-14-21)19-7-3-1-4-8-19)25-17-15-24(16-18-25)22-9-5-2-6-10-22/h1-14H,15-18H2 |
| InChIKey | VHYSKWYZIZGSJB-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1C2=CC=CC=C2)C(=O)C3=CC=C(C=C3)C4=CC=CC=C4 |
