PROTAC CDK2/9 Degrader-1

• CAT Number: I017374
• CAS Number: 2408641-24-5
• Molecular Formula: C₄₀H₄₁N₁₃O₇
• Molecular Weight: 815.84
• Purity: ≥95%

PROTAC CDK2/9 Degrader-1 (Cat.No:I017374) is a small molecule compound designed to selectively degrade cyclin-dependent kinase 2 (CDK2) and CDK9, which are important regulators of cell cycle progression and gene transcription. This PROTAC molecule recruits the ubiquitin-proteasome system to degrade the target proteins, offering potential therapeutic applications in cancer treatment and other diseases involving dysregulated CDK activity.

Reference

[1]. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2019 Dec 6;187:111952.