For research use only. Not for therapeutic Use.
PROTAC CDK9 ligand-1 is a CDK9 ligand that can be used in the synthesis of PROTACs.
| Catalog Number | I045567 |
| CAS Number | 3031327-95-1 |
| Synonyms | (2S)-2-[[7-[(4-aminophenyl)methylamino]-3-propan-2-ylpyrazolo[1,5-a]pyrimidin-5-yl]amino]butan-1-ol |
| Molecular Formula | C20H28N6O |
| Purity | ≥95% |
| InChI | InChI=1S/C20H28N6O/c1-4-16(12-27)24-18-9-19(22-10-14-5-7-15(21)8-6-14)26-20(25-18)17(11-23-26)13(2)3/h5-9,11,13,16,22,27H,4,10,12,21H2,1-3H3,(H,24,25)/t16-/m0/s1 |
| InChIKey | ZTQFEMJXWCDAAJ-INIZCTEOSA-N |
| SMILES | CCC(CO)NC1=NC2=C(C=NN2C(=C1)NCC3=CC=C(C=C3)N)C(C)C |
| Reference | [1]. Wei D, et al. Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer. J Med Chem. 2021 Oct 14;64(19):14822-14847. |
