For research use only. Not for therapeutic Use.
PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1].
| Catalog Number | I019066 |
| CAS Number | 2230826-81-8 |
| Molecular Formula | C₅₂H₆₁N₉O₉S₂ |
| Purity | ≥95% |
| Reference | [1]. Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140(48):16428-16432. |
