PROTAC IRAK3 degrade-1 formic

• CAT Number: I041234
• Molecular Formula: C48H65N11O8
• Molecular Weight: 924.10
• Purity: ≥95%
• Synonyms: 2-(2,6-dioxopiperidin-3-yl)-5-[4-[2-[1-[4-oxo-4-[4-[4-[(5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl)amino]cyclohexyl]piperazin-1-yl]butanoyl]piperidin-4-yl]ethyl]piperazin-1-yl]isoindole-1,3-dione;formic acid
• InChI: InChI=1S/C47H63N11O6.CH2O2/c1-31(2)36-16-20-57-43(36)44(48-30-49-57)50-33-3-5-34(6-4-33)53-25-27-56(28-26-53)42(61)12-11-41(60)55-18-14-32(15-19-55)13-17-52-21-23-54(24-22-52)35-7-8-37-38(29-35)47(64)58(46(37)63)39-9-10-40(59)51-45(39)62;2-1-3/h7-8,16,20,29-34,39H,3-6,9-15,17-19,21-28H2,1-2H3,(H,48,49,50)(H,51,59,62);1H,(H,2,3)
• InChIKey: BFLIYXLHZMYACM-UHFFFAOYSA-N
• SMILES: CC(C)C1=C2C(=NC=NN2C=C1)NC3CCC(CC3)N4CCN(CC4)C(=O)CCC(=O)N5CCC(CC5)CCN6CCN(CC6)C7=CC8=C(C=C7)C(=O)N(C8=O)C9CCC(=O)NC9=O.C(=O)O

PROTAC IRAK3 degrade-1 formic（Cat No.:I041234）is a small molecule that belongs to the PROTAC (proteolysis-targeting chimera) class of compounds. It is specifically designed to degrade IRAK3 (Interleukin-1 Receptor-Associated Kinase 3), a key regulator in immune and inflammatory responses. By inducing the targeted degradation of IRAK3, this compound has the potential to modulate immune signaling pathways, which could be beneficial for treating conditions like autoimmune diseases, inflammation, or cancer. The formic acid salt form enhances its stability and solubility, making it suitable for various biochemical and pharmacological studies.