Proteinase K

• CAT Number: I015394
• CAS Number: 39450-01-6
• Purity: ≥95%

Proteinase K (Cat No.: I015394) is a broad-spectrum serine protease widely used in molecular biology to digest proteins and remove contaminants from nucleic acid preparations. It is especially effective in degrading enzymes such as DNases and RNases, making it essential for high-quality DNA and RNA extraction. Active in a wide pH range and stable at elevated temperatures, Proteinase K remains effective in the presence of detergents and denaturants like SDS and urea. It is derived from the fungus Tritirachium album and is typically used in research applications.

Reference

[1]. W Ebeling, et al. Proteinase K From Tritirachium Album Limber. Eur J Biochem . 1974 Aug 15;47(1):91-7.
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[2]. Nosrati H, et al. Multifunctional nanoparticles from albumin for stimuli-responsive efficient dual drug delivery. Bioorg Chem. 2019 Jul;88:102959.
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[3]. Shukla A, et al. Vitality of Proteinase K in rRTPCR Detection of SARS-CoV2 Bypassing RNA Extraction. Front Cell Infect Microbiol. 2021 Nov 3;11:717068.
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[4]. Yu F, et al. Comparative Evaluation of Three Preprocessing Methods for Extraction and Detection of Influenza A Virus Nucleic Acids from Sputum. Front Med (Lausanne). 2018 Mar 2;5:56.
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