For research use only. Not for therapeutic Use.
Prothidathion(CAT: I035098) is a potent inhibitor targeting acetylcholinesterase (AChE), a critical enzyme involved in neurotransmitter regulation. By inhibiting AChE, Prothidathion effectively disrupts acetylcholine breakdown, resulting in prolonged neurotransmitter activity at synaptic junctions. This mechanism makes it a valuable tool in neuropharmacology for studying cholinergic signaling pathways, neurotoxicity, and the development of therapeutic agents for conditions like Alzheimer’s disease and other neurological disorders. Its precise activity allows researchers to explore enzyme kinetics, synaptic transmission, and neuroprotection strategies, providing crucial insights into the role of acetylcholinesterase in neuronal function and disease progression.
Catalog Number | I035098 |
CAS Number | 20276-83-9 |
Synonyms | Prothidathion; |
Molecular Formula | C10H19N2O4PS3 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | O,O-diethyl S-((5-isopropoxy-2-oxo-1,3,4-thiadiazol-3(2H)-yl)methyl) phosphorodithioate |
InChI | InChI=1S/C10H19N2O4PS3/c1-5-14-17(18,15-6-2)19-7-12-10(13)20-9(11-12)16-8(3)4/h8H,5-7H2,1-4H3 |
InChIKey | LQHMZSQJOYPNND-UHFFFAOYSA-N |
SMILES | S=P(OCC)(SCN1C(SC(OC(C)C)=N1)=O)OCC |