Protocatechuic acid

• CAT Number: I005743
• CAS Number: 99-50-3
• Molecular Formula: C7H6O4
• Molecular Weight: 154.12
• Purity: ≥95%
• Synonyms: Protocatechuic acid; 3,4-Dihydroxybenzoic acid
• Target: Endogenous Metabolite
• Solubility: DMSO
• Storage: -20°C
• IUPAC Name: 3,4-dihydroxybenzoic acid
• InChI: 1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)
• InChIKey: YQUVCSBJEUQKSH-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C=C1C(=O)O)O)O

Protocatechuic acid (Cat No.: I005743) is a naturally occurring phenolic compound found in various fruits, vegetables, and medicinal plants. Known for its antioxidant, anti-inflammatory, and antimicrobial properties, PCA plays a protective role in combating oxidative stress and cellular damage. It has been studied for its potential benefits in cardiovascular health, neuroprotection, cancer prevention, and metabolic regulation. PCA also influences key signaling pathways involved in inflammation and apoptosis. Its broad bioactivity makes it a valuable compound in pharmacological, nutraceutical, and functional food research.

Reference

[1]. Thakare VN, et al. Attenuation of acute restraint stress-induced depressive like behavior and hippocampal alterations with protocatechuic acid treatment in mice. Metab Brain Dis. 2016 Oct 26. 


[2]. Adefegha SA, et al. Alterations of Na+/K+-ATPase, cholinergic and antioxidant enzymes activity by protocatechuic acid in cadmium-induced neurotoxicity and oxidative stress in Wistar rats. Biomed Pharmacother. 2016 Oct;83:559-568. 


[3]. Hornedo-Ortega R, et al. Protocatechuic Acid: Inhibition of Fibril Formation, Destabilization of Preformed Fibrils of Amyloid-β and α-Synuclein, and Neuroprotection. J Agric Food Chem. 2016 Oct 10.