For research use only. Not for therapeutic Use.
PRT062607 Acetate (Cat No.: I034128), also known as P505-15, is a potent and selective inhibitor of spleen tyrosine kinase (Syk), a key regulator in B-cell receptor (BCR) and Fc receptor signaling. It is widely used in inflammation, autoimmune disease, and cancer research, particularly for studying diseases such as rheumatoid arthritis, lupus, and B-cell malignancies. By blocking Syk activity, PRT062607 Acetate suppresses immune cell activation and inflammatory responses. The acetate form enhances solubility and stability, making it valuable for in vitro and in vivo studies.
| CAS Number | 1370261-98-5 |
| Synonyms | acetic acid;2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[3-(triazol-2-yl)anilino]pyrimidine-5-carboxamide |
| Molecular Formula | C21H27N9O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C19H23N9O.C2H4O2/c20-15-6-1-2-7-16(15)26-19-22-11-14(17(21)29)18(27-19)25-12-4-3-5-13(10-12)28-23-8-9-24-28;1-2(3)4/h3-5,8-11,15-16H,1-2,6-7,20H2,(H2,21,29)(H2,22,25,26,27);1H3,(H,3,4)/t15-,16+;/m0./s1 |
| InChIKey | ISHXQLKRUSVKDD-IDVLALEDSA-N |
| SMILES | CC(=O)O.C1CCC(C(C1)N)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)N4N=CC=N4)C(=O)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
