PRX-08066 Maleic acid

• CAT Number: R061423
• CAS Number: 866206-55-5
• Molecular Formula: C19H17ClFN5S.C4H4O4
• Molecular Weight: 517.96
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: C1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N.C(=CC(=O)O)C(=O)O

PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2.

Reference

[1] Porvasnik SL, et al. J Pharmacol Exp Ther, 2010, 334(2), 364-372.
[2] Svejda B, et al. Cancer, 2010, 116(12), 2902-2912.
[3] Warburton R.R., et al. Online University.