For research use only. Not for therapeutic Use.
PS121912（Cat No.:I035115）is a selective and potent inhibitor of the enzyme monoacylglycerol lipase (MAGL), which plays a critical role in the hydrolysis of monoacylglycerols to free fatty acids and glycerol. By inhibiting MAGL, PS121912 can modulate the endocannabinoid system, particularly influencing the levels of 2-arachidonoylglycerol (2-AG), an important endocannabinoid. It is being studied for its potential therapeutic applications in neuroinflammation, pain management, and disorders involving the endocannabinoid system, such as epilepsy and anxiety. Ongoing research aims to assess its efficacy in various preclinical models and explore its broader clinical potential.
| CAS Number | 1529814-60-5 |
| Synonyms | N-[(4-methoxyphenyl)-(2-methyl-1H-indol-3-yl)methyl]-4-(trifluoromethyl)aniline |
| Molecular Formula | C24H21F3N2O |
| Purity | ≥95% |
| IUPAC Name | N-[(4-methoxyphenyl)-(2-methyl-1H-indol-3-yl)methyl]-4-(trifluoromethyl)aniline |
| InChI | InChI=1S/C24H21F3N2O/c1-15-22(20-5-3-4-6-21(20)28-15)23(16-7-13-19(30-2)14-8-16)29-18-11-9-17(10-12-18)24(25,26)27/h3-14,23,28-29H,1-2H3 |
| InChIKey | NNTQFFZNUZBJND-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=CC=CC=C2N1)C(C3=CC=C(C=C3)OC)NC4=CC=C(C=C4)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
