For research use only. Not for therapeutic Use.
Pseudouridimycin（Cat No.:I017958）, is a novel nucleoside antibiotic derived from Streptomyces. It exhibits potent antibacterial activity against a broad spectrum of bacteria, including drug-resistant strains. Pseudouridimycin inhibits bacterial RNA polymerase, the enzyme responsible for transcription, and effectively disrupts bacterial gene expression. This mechanism of action makes it a promising candidate for the development of new antibiotics to combat bacterial infections.
| Catalog Number | I017958 |
| CAS Number | 1566586-52-4 |
| Molecular Formula | C₁₇H₂₆N₈O₉ |
| Purity | ≥95% |
| Storage | Store at -20°C |
| IUPAC Name | (2S)-2-[[2-(diaminomethylideneamino)acetyl]-hydroxyamino]-N-[[(2R,3S,4R,5S)-5-(2,4-dioxo-1H-pyrimidin-5-yl)-3,4-dihydroxyoxolan-2-yl]methyl]pentanediamide |
| InChI | InChI=1S/C17H26N8O9/c18-9(26)2-1-7(25(33)10(27)5-22-16(19)20)15(31)21-4-8-11(28)12(29)13(34-8)6-3-23-17(32)24-14(6)30/h3,7-8,11-13,28-29,33H,1-2,4-5H2,(H2,18,26)(H,21,31)(H4,19,20,22)(H2,23,24,30,32)/t7-,8+,11+,12+,13-/m0/s1 |
| InChIKey | XDEYHXABZOKKDZ-YFKLLHAASA-N |
| SMILES | C1=C(C(=O)NC(=O)N1)C2C(C(C(O2)CNC(=O)C(CCC(=O)N)N(C(=O)CN=C(N)N)O)O)O |
| Reference | [1]. Rosenqvist P, et al. Characterization of C-nucleoside Antimicrobials from Streptomyces albus DSM 40763: Strepturidin is Pseudouridimycin. Sci Rep. 2019 Jun 20;9(1):8935. |
