For research use only. Not for therapeutic Use.
Psicofuranine(Cat No.:M122525)is a nucleoside antibiotic derived from Streptomyces species, primarily studied for its antitumor and antiviral properties. It functions by inhibiting purine nucleotide synthesis, effectively blocking DNA and RNA synthesis in cells, which hampers cell proliferation. Originally researched for its potential to treat leukemia, psicofuranine showed promising cytotoxic activity against certain cancer cells. However, due to toxicity concerns, its therapeutic use is limited, and it is mainly utilized in experimental research. Its unique mechanism of action continues to provide insights into cancer and antiviral drug development.
Catalog Number | M122525 |
CAS Number | 1874-54-0 |
Synonyms | 1/’-C-(hydroxymethyl)-adenosine |
Molecular Formula | C11H15N5O5 |
Purity | ≥95% |
Target | Bacterial |
Solubility | Soluble in DMSO |
Storage | Store at -20°C |
IUPAC Name | (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-2,5-bis(hydroxymethyl)oxolane-3,4-diol |
InChI | InChI=1S/C11H15N5O5/c12-9-6-10(14-3-13-9)16(4-15-6)11(2-18)8(20)7(19)5(1-17)21-11/h3-5,7-8,17-20H,1-2H2,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1 |
InChIKey | BNZYRKVSCLSXSJ-IOSLPCCCSA-N |
SMILES | C1=NC(=C2C(=N1)N(C=N2)[C@]3([C@@H]([C@@H]([C@H](O3)CO)O)O)CO)N |