For research use only. Not for therapeutic Use.
Psora-4 is a potent and selective inhibitor of Kv1.3 (voltage-gated potassium channels) with an EC50 of 3 nM[1]. Psora-4 has immunosuppressive activity and inhibits proliferation of human and rat myelin-specific effector memory T cells in vitro[2].
| Catalog Number | R058510 |
| CAS Number | 724709-68-6 |
| Synonyms | 4-(4-phenylbutoxy)furo[3,2-g]chromen-7-one |
| Molecular Formula | C21H18O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H18O4/c22-20-10-9-16-19(25-20)14-18-17(11-13-23-18)21(16)24-12-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-11,13-14H,4-5,8,12H2 |
| InChIKey | JJAWGNIQEOFURP-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CCCCOC2=C3C=CC(=O)OC3=CC4=C2C=CO4 |
| Reference | [1]. Vennekamp J, et al. Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators. Mol Pharmacol. 2004 Jun;65(6):1364-74. |
