PTBP1-RNA-binding inhibitor P6 TFA

• CAT Number: I040233
• Molecular Formula: C73H122N22O19.xC2HF3O2
• Molecular Weight: 1597.86 (free base)
• Purity: ≥95%

PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide inhibitor of the splicing factor PTBP1, which inhibits alternative splicing events regulated by PTBP1. PTBP1 binds RNA through its RNA recognition motif[1].

Reference

[1]. Schmeing S, et al. Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding. Chem Sci. 2023 Jul 13;14(31):8269-8278.
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