PU-H54

• CAT Number: I012282
• CAS Number: 1454619-13-6
• Molecular Formula: C18H19N5S
• Molecular Weight: 337.44
• Purity: ≥95%
• Synonyms: 8-(2,4-dimethylphenyl)sulfanyl-3-pent-4-ynyl-7H-purin-6-imine
• InChI: InChI=1S/C18H19N5S/c1-4-5-6-9-23-11-20-16(19)15-17(23)22-18(21-15)24-14-8-7-12(2)10-13(14)3/h1,7-8,10-11,19H,5-6,9H2,2-3H3,(H,21,22)
• InChIKey: GPYXPUQPGWULJH-UHFFFAOYSA-N
• SMILES: CC1=CC(=C(C=C1)SC2=NC3=C(N2)C(=N)N=CN3CCCC#C)C

PU-H54（Cat No.:I012282）is a small molecule inhibitor that targets the transcription factor MYC, which plays a critical role in regulating cell growth, proliferation, and metabolism. MYC is frequently dysregulated in various cancers, contributing to tumorigenesis and metastasis. PU-H54 works by disrupting the binding of MYC to its partner protein, thereby inhibiting its activity. This compound is being studied for its potential therapeutic applications in treating cancers where MYC is overexpressed or mutated, providing a targeted approach to inhibit tumor cell growth and enhance the efficacy of existing cancer therapies.