For research use only. Not for therapeutic Use.
Purfalcamine (Cat No.:I035223) is an orally active and selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with IC50 of 17nM and EC50 of 230nM. Purfalcamine has antimalarial activity and can cause the developmental arrest of Plasmodium in the schizont stage.
| Catalog Number | I035223 |
| CAS Number | 1038620-68-6 |
| Synonyms | Purfalcamine |
| Molecular Formula | C29H33FN8O |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| IUPAC Name | (4-((2-((4-Aminocyclohexyl)amino)-9-(3-fluorophenyl)-9H-purin-6-yl)amino)phenyl)(piperidin-1-yl)methanone |
| InChI | InChI=1S/C29H33FN8O/c30-20-5-4-6-24(17-20)38-18-32-25-26(35-29(36-27(25)38)34-23-13-9-21(31)10-14-23)33-22-11-7-19(8-12-22)28(39)37-15-2-1-3-16-37/h4-8,11-12,17-18,21,23H,1-3,9-10,13-16,31H2,(H2,33,34,35,36) |
| InChIKey | KRCOMOOXOZSNAJ-UHFFFAOYSA-N |
| SMILES | O=C(C1=CC=C(NC2=C3N=CN(C4=CC=CC(F)=C4)C3=NC(NC5CCC(N)CC5)=N2)C=C1)N6CCCCC6 |
