Puromycin-bis(PEG2-amide)-Biotin

• CAT Number: I041757
• CAS Number: 2379889-82-2
• Molecular Formula: C46H71N13O13S
• Molecular Weight: 1046.20
• Purity: ≥95%
• Synonyms: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[2-[2-[[(2S)-1-[[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]carbamoylamino]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethyl]pentanamide
• InChI: InChI=1S/C46H71N13O13S/c1-58(2)40-38-41(52-27-51-40)59(28-53-38)43-39(62)37(33(25-60)72-43)56-42(63)31(24-29-8-10-30(67-3)11-9-29)54-45(65)50-15-19-71-23-22-70-18-14-49-44(64)48-13-17-69-21-20-68-16-12-47-35(61)7-5-4-6-34-36-32(26-73-34)55-46(66)57-36/h8-11,27-28,31-34,36-37,39,43,60,62H,4-7,12-26H2,1-3H3,(H,47,61)(H,56,63)(H2,48,49,64)(H2,50,54,65)(H2,55,57,66)/t31-,32-,33+,34-,36-,37+,39+,43+/m0/s1
• InChIKey: UIXBHXLEEBYWHU-VSRHOESXSA-N
• SMILES: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)NC(=O)NCCOCCOCCNC(=O)NCCOCCOCCNC(=O)CCCCC5C6C(CS5)NC(=O)N6)O

Puromycin-bis(PEG2-amide)-Biotin is used for single-cell translatome sequencing[1].

Reference

[1]. Yungui Yang, et al. Single-cell translatome sequencing method. WO2023284076A1.