PX-866

• CAT Number: R024647
• CAS Number: 502632-66-8
• Molecular Formula: C₂₉H₃₅NO₈
• Molecular Weight: 525.59
• Purity: ≥95%
• Synonyms: 5-(acetyloxy)-1-[(di-2-propenylamino)methylene]-4,4a,5,6,6a,8,9,9a-octahydro-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-cyclopenta[5,6]naphtho[1,2-c]pyran-2,7,10(1H)-trione
• Target: PI3K
• IUPAC Name: [(3aR,6E,9S,9aR,10R,11aS)-6-[[bis(prop-2-enyl)amino]methylidene]-5-hydroxy-9-(methoxymethyl)-9a,11a-dimethyl-1,4,7-trioxo-2,3,3a,9,10,11-hexahydroindeno[4,5-h]isochromen-10-yl] acetate
• InChI: InChI=1S/C29H35NO8/c1-7-11-30(12-8-2)14-17-23-26(34)25(33)22-18-9-10-20(32)28(18,4)13-19(37-16(3)31)24(22)29(23,5)21(15-36-6)38-27(17)35/h7-8,14,18-19,21,34H,1-2,9-13,15H2,3-6H3/b17-14+/t18-,19+,21+,28-,29-/m0/s1
• InChIKey: QIUASFSNWYMDFS-NILGECQDSA-N
• SMILES: CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C(=CN(CC=C)CC=C)C4=C(C3=O)O)COC)C)C

PX-866（Cat No.:R024647）is a potent and selective inhibitor of phosphoinositide 3-kinase (PI3K), a crucial enzyme involved in cell growth, proliferation, and survival pathways. By targeting PI3K, PX-866 shows promise in cancer treatment, particularly in tumors with aberrant PI3K signaling. This compound has been extensively studied for its ability to enhance the efficacy of chemotherapy and radiotherapy. High-purity PX-866 is vital for preclinical and clinical research, providing reliable and consistent results in studies aimed at developing targeted cancer therapies and understanding the molecular mechanisms of tumor growth.