For research use only. Not for therapeutic Use.
PXS-4728A (BI-1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO). PXS-4728A ameliorates chronic obstructive pulmonary disease in mice[1].
| Catalog Number | I008921 |
| CAS Number | 1478364-68-9 |
| Synonyms | 4-[(E)-2-(aminomethyl)-3-fluoroprop-2-enoxy]-N-tert-butylbenzamide;hydrochloride |
| Molecular Formula | C15H22ClFN2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H21FN2O2.ClH/c1-15(2,3)18-14(19)12-4-6-13(7-5-12)20-10-11(8-16)9-17;/h4-8H,9-10,17H2,1-3H3,(H,18,19);1H/b11-8+; |
| InChIKey | AEMZEDNMNLIDSL-YGCVIUNWSA-N |
| SMILES | CC(C)(C)NC(=O)C1=CC=C(C=C1)OCC(=CF)CN.Cl |
| Reference | [1]. A G Jarnicki, et al. The Inhibitor of Semicarbazide-Sensitive Amine Oxidase, PXS-4728A, Ameliorates Key Features of Chronic Obstructive Pulmonary Disease in a Mouse Model. Br J Pharmacol. 2016 Nov;173(22):3161-3175. |
