Pyrantel tartrate

• CAT Number: I003211
• CAS Number: 33401-94-4
• Molecular Formula: C15H20N2O6S
• Molecular Weight: 356.39
• Purity: ≥95%
• Target: Neuronal Signaling
• Solubility: DMSO: ≥ 34 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (2R,3R)-2,3-dihydroxybutanedioic acid;1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine
• InChI: InChI=1S/C11H14N2S.C4H6O6/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10;5-1(3(7)8)2(6)4(9)10/h2,4-6,9H,3,7-8H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/b6-5+;/t;1-,2-/m.1/s1
• InChIKey: VWRCYAZJKNPEQR-NIEARKAZSA-N
• SMILES: CN1CCCN=C1/C=C/C2=CC=CS2.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O

Pyrantel tartrate（Cat No.:I003211）is a widely used anthelmintic compound effective against gastrointestinal nematodes. It works by acting as a neuromuscular blocking agent, causing spastic paralysis in susceptible parasites, leading to their expulsion from the host’s system. This tartrate salt form enhances solubility and stability, making it suitable for oral administration in veterinary and human applications. Pyrantel tartrate is particularly effective against pinworms, roundworms, and hookworms, with minimal absorption into the bloodstream, reducing systemic side effects. Its broad spectrum and safety profile make it a preferred choice in parasitic infection control.

Reference

[1]. Aceves J, et al. The mechanism of the paralysing action of tetramisole on Ascaris somatic muscle. Br J Pharmacol. 1970 May;38(3):602-7.
[2]. Aubry ML, et al. Aspects of the pharmacology of a new anthelmintic: pyrantel. Br J Pharmacol. 1970 Feb;38(2):332-44.