For research use only. Not for therapeutic Use.
Pyrazinamide（Cat No.:A000469）is an essential antibiotic used in combination therapy to treat active tuberculosis (TB). It specifically targets Mycobacterium tuberculosis by inhibiting fatty acid synthase I, disrupting bacterial cell membrane synthesis and energy production. Pyrazinamide is particularly effective in the initial intensive phase of TB treatment, helping to shorten overall therapy duration. It is well-absorbed orally and penetrates well into tissues, including the lungs. Common side effects include liver toxicity and joint pain, necessitating regular monitoring. Its critical role in TB treatment makes Pyrazinamide indispensable in global TB control efforts.
| Catalog Number | A000469 |
| CAS Number | 98-96-4 |
| Synonyms | Pyrazinoic Acid Amide |
| Molecular Formula | C5H5N3O |
| Purity | ≥95% |
| Target | Autophagy |
| Solubility | >5.4mg/mL in DMSO |
| Storage | 3 years -20C powder |
| IUPAC Name | pyrazine-2-carboxamide |
| InChI | InChI=1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9) |
| InChIKey | IPEHBUMCGVEMRF-UHFFFAOYSA-N |
| SMILES | C1=CN=C(C=N1)C(=O)N |
