For research use only. Not for therapeutic Use.
Pyrazinamide-d3（Cat No.:S000482） is a deuterated form of pyrazinamide, an important antitubercular medication used in the treatment of tuberculosis. In this deuterated version, three hydrogen atoms are replaced with deuterium, a heavier isotope of hydrogen, which can influence the drug’s metabolic stability and pharmacokinetic profile. Pyrazinamide is a prodrug that is converted into its active form pyrazinoic acid in the body, crucial for its bactericidal activity against Mycobacterium tuberculosis. The deuteration in pyrazinamide-d3 is utilized in pharmacological studies to explore how these modifications affect its efficacy and metabolism.
| Catalog Number | S000482 |
| CAS Number | 1432059-16-9 |
| Molecular Formula | C5H2D3N3O |
| Purity | ≥95% |
| IUPAC Name | 3,5,6-trideuteriopyrazine-2-carboxamide |
| InChI | InChI=1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)/i1D,2D,3D |
| InChIKey | IPEHBUMCGVEMRF-CBYSEHNBSA-N |
| SMILES | C1=CN=C(C=N1)C(=O)N |
