Pyridostigmine Bromide

• CAT Number: A000354
• CAS Number: 101-26-8
• Molecular Formula: C9H13BrN2O2
• Molecular Weight: 261.12
• Purity: ≥95%
• Synonyms: Mestinon; 101-26-8; Regonol; Kalimin; Kalymin
• Target: Cholinesterase (ChE)
• Solubility: Soluble in DMSO > 10 mM
• Storage: -20°C
• InChI: 1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1
• InChIKey: VNYBTNPBYXSMOO-UHFFFAOYSA-M
• SMILES: C[N+]1=CC=CC(=C1)OC(=O)N(C)C.[Br-]

Pyridostigmine Bromide is a cholinesterase inhibitor with a slightly longer duration of action than neostigmine. It is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.Pyridostigmine bromide binds reversibly to acetylcholinesterase active sites in the peripheral nervous system, thereby preventing the breakdown of acetylcholine. This leads to an accumulation of acetylcholine at cholinergic synapses and facilitates transmission of impulses across the neuromuscular junction.

Reference

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