Pyridoxal-d5 5’-Phosphate

• CAT Number: R047924
• CAS Number: 1246818-16-5
• Molecular Formula: C8H10NO6P
• Molecular Weight: 252.173
• Purity: ≥95%
• Synonyms: 3-Hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde-d5; Pyridoxal-d5 Phosphate; Pyridoxal-d5 5-(Dihydrogen Phosphate); 2-Methyl-3-hydroxy-4-formyl-5-pyridyl-methylphosphoric Acid-d5; 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinalde
• Storage: -20°C
• IUPAC Name: [dideuterio-[4-formyl-5-hydroxy-6-(trideuteriomethyl)pyridin-3-yl]methyl] dihydrogen phosphate
• InChI: InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)/i1D3,4D2
• InChIKey: NGVDGCNFYWLIFO-SGEUAGPISA-N
• SMILES: [2H]C([2H])([2H])C1=NC=C(C(=C1O)C=O)C([2H])([2H])OP(=O)(O)O

Pyridoxal-d5 5′-Phosphate is a deuterated form of pyridoxal 5′-phosphate (PLP), where five hydrogen atoms are replaced with deuterium. PLP is the active form of vitamin B6 and serves as a coenzyme in various enzymatic reactions, particularly those involved in amino acid metabolism. The deuterium labeling in Pyridoxal-d5 5′-Phosphate allows for precise tracking in biochemical and metabolic studies, using techniques like mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. This compound is particularly useful in research focused on vitamin B6 metabolism, enzyme mechanisms, and the role of PLP in physiological and pathological processes. Pyridoxal-d5 5′-Phosphate provides researchers with reliable data for understanding the complex biochemical pathways involving PLP and for developing therapeutic strategies targeting vitamin B6-dependent enzymes.