For research use only. Not for therapeutic Use.
Pyrimorph is a fungicide with excellent antifungal activity against oomycetes[1].
Pyrimorph inhibits different stages in the life cycle of P.capsici: mycelial growth (EC50 = 1.84 μg/mL), sporangia formation (EC50 = 0.17 μg/mL), zoospore release (EC50 = 4.92 μg/mL), cystospore germination (EC50 = 0.09 μg/mL)[1].
Pyrimorph exhibits 40.95% inhibition of oxygen consumption of intact mycelia at 100 μg/mL[1].
Pyrimorph inhibits the synthesis of cell wall either directly or indirectly from ultrastructural transformation of cell wall thickening and disruption of vacuoles[1].
Pyrimorph (0-28 mg/L; exposure; 0-192 h) has low toxicity and accumulates quickly in zebrafish[2].
| Catalog Number | I035266 |
| CAS Number | 868390-90-3 |
| Synonyms | (E)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-1-morpholin-4-ylprop-2-en-1-one |
| Molecular Formula | C22H25ClN2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H25ClN2O2/c1-22(2,3)18-6-4-16(5-7-18)19(17-8-9-24-20(23)14-17)15-21(26)25-10-12-27-13-11-25/h4-9,14-15H,10-13H2,1-3H3/b19-15+ |
| InChIKey | QEUOHPLVFSQWME-XDJHFCHBSA-N |
| SMILES | CC(C)(C)C1=CC=C(C=C1)C(=CC(=O)N2CCOCC2)C3=CC(=NC=C3)Cl |
| Reference | [1]. Xiaojing Yan, et al. Study of inhibitory effects and action mechanism of the novel fungicide pyrimorph against Phytophthora capsici. J Agric Food Chem. 2010 Mar 10;58(5):2720-5. [2]. Chunqing Zhao, et al. Acute toxicity and bioconcentration of pyrimorph in zebrafish, Brachydanio rerio. Pest Manag Sci. 2011 Sep;67(9):1178-83. |
