Pyrrocaine

• CAT Number: I035280
• CAS Number: 2210-77-7
• Molecular Formula: C14H20N2O
• Molecular Weight: 232.33
• Purity: 98%
• Synonyms: Pyrrocaine; EN-1010; EN1010; EN 1010; NSC52644; NSC-52644; NSC 52644
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1-Pyrrolidineacetamide, N-(2,6-dimethylphenyl)-
• InChI: InChI=1S/C14H20N2O/c1-11-6-5-7-12(2)14(11)15-13(17)10-16-8-3-4-9-16/h5-7H,3-4,8-10H2,1-2H3,(H,15,17)
• InChIKey: OYCGKECKIVYHTN-UHFFFAOYSA-N
• SMILES: O=C(NC1=C(C)C=CC=C1C)CN2CCCC2

Pyrrocaine is an anesthetic (Local)

Reference

1: Olech E. Pyrrocaine HCl – A Preliminary Clinical Study of Its Uses in Oral Surgery. J Am Dent Soc Anesthesiol. 1963 Oct;10(8):224-9. PMID: 19598995; PMCID: PMC2067883.
2: Zsigmond EK, Patterson RL. Double-blind evaluation of a new local anesthetic agents, pyrrocaine hydrochloride, for nerve block anesthesia. Anesth Analg. 1969 Jan-Feb;48(1):66-74. PMID: 4883831.
3: de Verneuil H, Deybach JC, Phung N, Da Silva V, Nordmann Y. Study of anaesthetic agents for their ability to elicit porphyrin biosynthesis in chick embryo liver. Biochem Pharmacol. 1983 Mar 15;32(6):1011-8. doi: 10.1016/0006-2952(83)90619-6. PMID: 6838647.
4: de Freitas JF. A rapid spectrophotometric assay of amide type dental anaesthetic agents. Aust Dent J. 1977 Jun;22(3):182-9. doi: 10.1111/j.1834-7819.1977.tb04486.x. PMID: 270977.