For research use only. Not for therapeutic Use.
Pyrroxamycin is a new antibiotic. Pyrroxamycin was isolated from the culture broth of Streptomyces sp. S46506. Pyrroxamycin is active against Gram-positive bacteria and dermatophytes.
| Catalog Number | M013275 |
| CAS Number | 105888-54-8 |
| Molecular Formula | C12H6Cl4N2O4 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 2,3-dichloro-5-[(4S)-6,8-dichloro-4H-1,3-benzodioxin-4-yl]-4-nitro-1H-pyrrole |
| InChI | InChI=1S/C12H6Cl4N2O4/c13-4-1-5-10(6(14)2-4)21-3-22-11(5)8-9(18(19)20)7(15)12(16)17-8/h1-2,11,17H,3H2/t11-/m0/s1 |
| InChIKey | CUPRKSFMHRXAFA-NSHDSACASA-N |
| SMILES | C1OC(C2=CC(=CC(=C2O1)Cl)Cl)C3=C(C(=C(N3)Cl)Cl)[N+](=O)[O-] |
| Reference | 1:J Antibiot (Tokyo). 1987 Jul;40(7):961-9. Pyrroxamycin, a new antibiotic taxonomy, fermentation, isolation, structure determination and biological properties.Yano K,Oono J,Mogi K,Asaoka T,Nakashima T, PMID: 3624075 </br><span>Abstract:</span> A strain of streptomycete was found to produce a new antibiotic pyrroxamycin. This compound was isolated from the culture broth of Streptomyces sp. S46506. The chemical structure was determined to be 4,5-dichloro-2-(6/’,8/’-dichloro-4/’H-1/’,3/’-benzodioxin-4/’-yl)-3-nitr opyrrole by its chemical character and 1H and 13C NMR spectral analysis. Pyrroxamycin was active against Gram-positive bacteria and dermatophytes. |
