For research use only. Not for therapeutic Use.
PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC50 value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents[1].
| Catalog Number | I035290 |
| CAS Number | 1821370-71-1 |
| Synonyms | 2-(5-carboxypyridin-2-yl)-1,3-thiazole-5-carboxylic acid |
| Molecular Formula | C10H6N2O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C10H6N2O4S/c13-9(14)5-1-2-6(11-3-5)8-12-4-7(17-8)10(15)16/h1-4H,(H,13,14)(H,15,16) |
| InChIKey | ISYUGJYTQIZJHV-UHFFFAOYSA-N |
| SMILES | C1=CC(=NC=C1C(=O)O)C2=NC=C(S2)C(=O)O |
| Reference | [1]. Vasta JD, et al. Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. ACS Chem Biol. 2016 Jan 15;11(1):193-9. |
