Quensyl-1-acetate

• CAT Number: C000740
• CAS Number: 47493-14-1
• Molecular Formula: C₂₀H₂₈ClN₃O₂
• Molecular Weight: 377.91
• Purity: ≥95%
• Synonyms: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol 1-Acetate; 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethyl Acetate
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• Appearance: Colourless to Beige Oil to Solid
• Storage: 4°C
• IUPAC Name: 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethyl acetate
• InChI: InChI=1S/C20H28ClN3O2/c1-4-24(12-13-26-16(3)25)11-5-6-15(2)23-19-9-10-22-20-14-17(21)7-8-18(19)20/h7-10,14-15H,4-6,11-13H2,1-3H3,(H,22,23)
• InChIKey: YEVQTWFAUWKTAU-UHFFFAOYSA-N
• SMILES: CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCOC(=O)C

Quensyl-1-acetate (Cat No.:C000740) is a chemical compound that likely involves the modification or derivatization of Quensyl, also known as hydroxychloroquine or chloroquine. These compounds are primarily used as antimalarial drugs and have also shown efficacy in treating autoimmune conditions like rheumatoid arthritis and systemic lupus erythematosus. The addition of the acetate group may alter the compound’s properties, potentially affecting its solubility, bioavailability, or pharmacokinetics.

Reference

Yarden, Y., et al.: Nature, 323, 226 (1986);