Quillaic acid

• CAT Number: I004379
• CAS Number: 631-01-6
• Molecular Formula: C30H46O5
• Molecular Weight: 486.68
• Purity: ≥95%
• Target: Apoptosis
• Solubility: DMSO: 40 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (4aR,5R,6aR,6aS,6bR,8aR,9S,10S,12aR,14bS)-9-formyl-5,10-dihydroxy-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
• InChI: InChI=1S/C30H46O5/c1-25(2)13-14-30(24(34)35)19(15-25)18-7-8-21-26(3)11-10-22(32)27(4,17-31)20(26)9-12-28(21,5)29(18,6)16-23(30)33/h7,17,19-23,32-33H,8-16H2,1-6H3,(H,34,35)/t19-,20+,21+,22-,23+,26-,27-,28+,29+,30+/m0/s1
• InChIKey: MQUFAARYGOUYEV-UAWZMHPWSA-N
• SMILES: C[C@]12CC[C@@H]([C@@]([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(C[C@H]([C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)O)C)C)(C)C=O)O

Quillaic acid（Cat No.:I004379）is a naturally occurring triterpenoid saponin found in the bark of Quillaja saponaria, commonly known as the soapbark tree. It has been studied for its immunological and pharmacological properties, particularly as an adjuvant in vaccine formulations. Quillaic acid stimulates immune responses by activating immune cells and enhancing antigen presentation, making it useful in vaccine development. Additionally, it exhibits antimicrobial, anti-inflammatory, and antioxidant activities, which could have therapeutic applications in treating infections and inflammatory diseases. Its ability to modulate the immune system has garnered interest for various biomedical applications.

Reference

[1]. Arrau S, et al. Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice. J Ethnopharmacol. 2011 Jan 7;133(1):164-7.

[2]. Rodríguez-Díaz M, et al. Topical anti-inflammatory activity of quillaic acid from Quillaja saponaria Mol. and some derivatives. J Pharm Pharmacol. 2011 May;63(5):718-24.