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525-61-1-Quinocide Quinocide

Quinocide

For research use only. Not for therapeutic Use.

  • CAT Number: M004518
  • CAS Number: 525-61-1
  • Molecular Formula: C15H21N3O
  • Molecular Weight: 259.353
  • Purity: ≥95%
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Related Small Molecules: PEG 200 monooleate     N-Boc-p-nitro-L-phenylalanine     1-(4-Ethoxycarbonylphenyl)piperazine    

Quinocide (Cat.No:M004518) is a chemical compound that has been studied for its potential as an antimalarial agent. It belongs to the class of quinoline derivatives. Quinocide’s mechanism of action involves interfering with the metabolism of the malaria parasite, making it a subject of interest in the search for new treatments against this infectious disease.


Catalog Number M004518
CAS Number 525-61-1
Synonyms

Quinocide;8-[(4-Aminopentyl)amino]-6-methoxyquinoline;Khinocyde;N-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine;1-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine;4-aminopentyl-(6-methoxy-8-quinolyl)amine;N1-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine;Pri

Molecular Formula C15H21N3O
Purity ≥95%
Storage -20°C
IUPAC Name 1-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
InChI InChI=1S/C15H21N3O/c1-11(16)5-3-7-17-14-10-13(19-2)9-12-6-4-8-18-15(12)14/h4,6,8-11,17H,3,5,7,16H2,1-2H3
InChIKey NBAFIBBHADOTMU-UHFFFAOYSA-N
SMILES CC(CCCNC1=C2C(=CC(=C1)OC)C=CC=N2)N
Reference

1: LYSENKO AY. Use of quinocide in treatment and prophylaxis of vivax malaria. Bull World Health Organ. 1960;22:641-62. PubMed PMID: 14419205; PubMed Central PMCID: PMC2555349.<br />
2: Marutian EM. [Testing Quinocide and other preparations in theileriasis]. Veterinariia. 1968 Jul;45(7):50-1. Russian. PubMed PMID: 5736460.<br />
3: Elbashir AA, Saad B, Ali AS, Saleh MI, Aboul-Enein HY. Enantioselective analysis of primaquine and its impurity quinocide by capillary electrophoresis. Biomed Chromatogr. 2009 Mar;23(3):295-301. doi: 10.1002/bmc.1113. PubMed PMID: 18816453.<br />
4: Pereponov GA. [The efficacy of quinocide and bigumal in theileriasis]. Veterinariia. 1967 Apr;44(4):50-1. Russian. PubMed PMID: 5629495.<br />
5: GLADKIKH VF, KOROGODINA IuV. [Toxicological and certain pharmacodynamic properties of quinocide]. Med Parazitol (Mosk). 1960 Jul-Aug;29:440-7. Russian. PubMed PMID: 13705882.<br />
6: Elbashir AA, Saad B, Ali AS, Saleh MI, Aboul-Enein HY. Determination of quinocide as impurity in primaquine tablets by capillary zone electrophoresis. Biomed Chromatogr. 2009 May;23(5):464-71. doi: 10.1002/bmc.1137. PubMed PMID: 19016231.<br />
7: CHECHEL/&#39;NITSKAIA SM, BAIGULOVA SA. [Effectiveness of quinocide in the treatment of tertian malaria]. Med Parazitol (Mosk). 1957 May-Jun;26(3):268-9. Russian. PubMed PMID: 13482775.

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