Quisinostat (JNJ-26481585) 2HCl

• CAT Number: I006448
• CAS Number: 875320-31-3
• Molecular Formula: C21H28Cl2N6O2
• Molecular Weight: 467.39
• Purity: ≥95%
• Target: HDAC1
• Storage: 3 years -20℃ powder
• IUPAC Name: N-hydroxy-2-[4-[[(1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]pyrimidine-5-carboxamide;dihydrochloride
• InChI: InChI=1S/C21H26N6O2.2ClH/c1-26-14-17(18-4-2-3-5-19(18)26)11-22-10-15-6-8-27(9-7-15)21-23-12-16(13-24-21)20(28)25-29;;/h2-5,12-15,22,29H,6-11H2,1H3,(H,25,28);2*1H
• InChIKey: NRUIZESXVMJDKR-UHFFFAOYSA-N
• SMILES: CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO.Cl.Cl

Quisinostat (JNJ-26481585) 2HCl（Cat No.:I006448）is a potent histone deacetylase (HDAC) inhibitor that plays a critical role in epigenetic regulation, making it a valuable compound in cancer research. By inhibiting HDAC enzymes, it promotes the acetylation of histones, leading to altered gene expression and potential tumor suppression. This compound shows promise in treating various malignancies, including hematologic cancers. The hydrochloride salt form enhances its solubility and bioavailability, facilitating its use in both in vitro and in vivo studies. Quisinostat is instrumental in advancing therapeutic strategies against cancer.