QUN 66708

• CAT Number: I035362
• CAS Number: 2169266-70-8
• Molecular Formula: C21H24N2O7
• Molecular Weight: 416.43
• Purity: 98%
• Synonyms: Thalidomide 4'-ether-alkylC7-acid; QUN 66708; QUN-66708; QUN66708
• Target: Autophagy
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 8-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyoctanoic acid
• InChI: InChI=1S/C21H24N2O7/c24-16-11-10-14(19(27)22-16)23-20(28)13-7-6-8-15(18(13)21(23)29)30-12-5-3-1-2-4-9-17(25)26/h6-8,14H,1-5,9-12H2,(H,25,26)(H,22,24,27)
• InChIKey: QFRXURXVZYAHGC-UHFFFAOYSA-N
• SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCCCCCCCC(=O)O

QUN 66708（Cat No.:I035362）is a small molecule inhibitor that selectively targets and inhibits the enzyme leucyl-tRNA synthetase (LRS). LRS plays a key role in protein synthesis by catalyzing the attachment of leucine to its corresponding tRNA molecule. Inhibition of LRS can interfere with protein translation and cellular processes, making QUN 66708 valuable in research related to protein synthesis and cellular regulation. It is particularly used in studies exploring the role of leucyl-tRNA synthetase in cancer, neurodegenerative diseases, and other conditions where protein synthesis is dysregulated. Its therapeutic potential is still under investigation.