For research use only. Not for therapeutic Use.
QUN-70738 is a negative control for ERK Inhibitor II. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
| Catalog Number | I035363 |
| CAS Number | 1177970-73-8 |
| Synonyms | QUN-70738; QUN70738; QUN 70738; FR180204 negative control; FR 180204 negative control; FR-180204 negative control; ERK Inhibitor II, Negative Control; |
| Molecular Formula | C18H12N6O |
| Purity | 98% |
| Target | Stem Cell/Wnt |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1,2-dihydro-3H-pyrazolo[3,4-c]pyridazin-3-one |
| InChI | InChI=1S/C18H12N6O/c25-18-12-10-13(19-20-17(12)21-22-18)15-14-8-4-5-9-24(14)23-16(15)11-6-2-1-3-7-11/h1-10H,(H2,20,21,22,25) |
| InChIKey | QMBDONCHHMIWFJ-UHFFFAOYSA-N |
| SMILES | O=C1NNC2=NN=C(C3=C4C=CC=CN4N=C3C5=CC=CC=C5)C=C21 |
| Reference | 1: Chen-Roetling J, Li Z, Chen M, Awe OO, Regan RF. Heme oxygenase activity and hemoglobin neurotoxicity are attenuated by inhibitors of the MEK/ERK pathway. Neuropharmacology. 2009 Apr;56(5):922-8. doi: 10.1016/j.neuropharm.2009.01.022. Epub 2009 Feb 6. PMID: 19371583; PMCID: PMC2692087. |
