For research use only. Not for therapeutic Use.
MT-<wbr></wbr>45 (Item No. <span class=/itemid/>14082</span>) is a piperazine derivative with potent analgesic activity comparable to morphine despite being structurally unrelated to most other opioids. (R)-<wbr></wbr>(−)-<wbr></wbr>MT-<wbr></wbr>45 is an enantiomer of MT-<wbr></wbr>45 that displays less analgesic potency than that of morphine or the (S)-<wbr></wbr>(+) enantiomer (Item No. <span class=/itemid/>15128</span>; ED<sub>50</sub>s = 2.0, 0.4, and 0.35 μg/kg, i.v., respectively, in Haffner’s mouse tail-<wbr></wbr>pinch method). This product is intended for forensic and research applications.
| Catalog Number | R064982 |
| CAS Number | 57426-38-7 |
| Synonyms | 1-cyclohexyl-4-[(1R)-1,2-diphenylethyl]-piperazine, dihydrochloride |
| Molecular Formula | C24H34Cl2N2 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 1-cyclohexyl-4-[(1R)-1,2-diphenylethyl]piperazine;dihydrochloride |
| InChI | InChI=1S/C24H32N2.2ClH/c1-4-10-21(11-5-1)20-24(22-12-6-2-7-13-22)26-18-16-25(17-19-26)23-14-8-3-9-15-23;;/h1-2,4-7,10-13,23-24H,3,8-9,14-20H2;2*1H/t24-;;/m1../s1 |
| InChIKey | PDTBWROWBIVSFO-PPLJNSMQSA-N |
| SMILES | C1CCC(CC1)N2CCN(CC2)C(CC3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl |
| Reference | 1.Natsuka, K.,Nakamura, H.,Uno, H., et al. Studies on 1-substituted 4-(1,2-diphenylethyl)piperazine derivatives and their analgesic activities. 1. Journal of Medicinal Chemistry 18(12), 1240-1244 (1975). |
