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((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone
For research use only. Not for therapeutic Use.
((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone(CAT: C000308) plays a role in pharmaceuticals, specifically in the context of urinary incontinence treatment. It is identified as a potential impurity of solifenacin, a muscarinic M3 receptor antagonist utilized for managing urinary incontinence. This compound’s presence as an impurity necessitates meticulous quality control during solifenacin’s synthesis and formulation.
Catalog Number | C000308 |
CAS Number | 2216750-52-4 |
Synonyms | Solifenacin Impurity D |
Molecular Formula | C₃₁H₂₈N₂O |
Purity | ≥95% |
Solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly) |
Appearance | White to Off-White Solid |
Storage | 4°C |
Reference | Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006) |