(R)-2-Amino-N-benzyl-3-methoxypropionamide

• CAT Number: R043125
• CAS Number: 196601-69-1
• Molecular Formula: C11H16N2O2
• Molecular Weight: 208.261
• Purity: ≥95%
• Synonyms: (2R)-2-Amino-3-methoxy-N-(phenylmethyl)-propanamide;?(R)-2-Amino-3-methoxy-N-(phenylmethyl)-propanamide; (2R)-2-Amino-3-methoxy-N-(phenylmethyl)propanamide; (2R)-2-Amino-N-benzyl-3-methoxypropanamide
• Storage: -20°C
• IUPAC Name: (2R)-2-amino-N-benzyl-3-methoxypropanamide
• InChI: InChI=1S/C11H16N2O2/c1-15-8-10(12)11(14)13-7-9-5-3-2-4-6-9/h2-6,10H,7-8,12H2,1H3,(H,13,14)/t10-/m1/s1
• InChIKey: WPLANNRKFDHEKD-SNVBAGLBSA-N
• SMILES: COCC(C(=O)NCC1=CC=CC=C1)N

(R)-2-Amino-N-benzyl-3-methoxypropionamide (CAS 196601-69-1) is an impurity of Lacosamide which is a potent anticonvulsant.

Reference

1.LeTiran, Arnaud, James P. Stables, and Harold Kohn. "Design and evaluation of affinity labels of functionalized amino acid anticonvulsants." Journal of medicinal chemistry 45.21 (2002): 4762-4773.
2.Wadavrao, Sachin B., Ashritha Narikimalli, and A. Venkat Narsaiah. "A Non-infringing Route for Enantioselective Synthesis of Antiepileptic Agent Lacosamide." Synthesis 45.24 (2013): 3383-3386.