(R)-2-Methyl-1-tosylaziridine

• CAT Number: C000282
• CAS Number: 177971-32-3
• Molecular Formula: C₁₀H₁₃NO₂S
• Molecular Weight: 211.28
• Purity: ≥95%
• Synonyms: (R)-2-Methyl-1-[(4-methylphenyl)sulfonyl]-aziridine; (R)-2-Methyl-1-tosylaziridine; (2R)-2-Methyl-1-[(4-methylphenyl)sulfonyl]aziridine
• Solubility: Chloroform (Sparingly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Inert atmosphere

(R)-2-Methyl-1-tosylaziridine(CAT: C000282) finds utility in organic synthesis due to its versatile reactivity. It serves as a building block for the construction of various heterocyclic compounds, including tetrahydropyridines, morpholines, chiral b- and γ-amino ethers, and (ent)-korupensamine D. The latter compound, (ent)-korupensamine D, is a natural product known for its antimalarial properties.

Reference

Ghorai, M. K., et al.: J. Org. Chem. 77, 3740 (2012); Pattenden, L. C., et al.: Org. Lett. 8, 3089 (2006); Hallock, Y. F., et al.: J. Nat. Prod. 60, 677 (1997)