For research use only. Not for therapeutic Use.
<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">(R)-(+)-2-Methyl-CBS-oxazaborolidine (CAS 112022-83-0) <span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">is a chemical employed in the asymmetric reduction of prochiral ketones. </span><span style="orphans: 2; widows: 2;">Studies indicate that (R)-(+)-2-Methyl-CBS-oxazaborolidine is useful in the production of stereospecific motifs such as α-hydroxy acids, α-amino acids, symmetrical ferrocenyl diols and propargyl alcohols. We also offer (R)-(+)-oxazaborolidine (sc-258069), which can be used to synthesize enantiospecific products.</span></span></span></span>
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| Catalog Number | R027124 |
| CAS Number | 112022-83-0 |
| Synonyms | (3aR)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole; (R)-(+)-2-Methyl-CBS-oxazaborolidine; (R)-2-Methyl-CBS-oxazaborolidine; (R)-Me-CBS; (R)-Me-Corey-Bakshi-Shibata reagent; (R)-Methyl-CBS; (R)-Tetrahydro-1-methyl-3,3-diphen |
| Molecular Formula | C18H20BNO |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | (3aR)-1-methyl-3,3-diphenyl-3a,4,5,6-tetrahydropyrrolo[1,2-c][1,3,2]oxazaborole |
| InChI | InChI=1S/C18H20BNO/c1-19-20-14-8-13-17(20)18(21-19,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17H,8,13-14H2,1H3/t17-/m1/s1 |
| InChIKey | VMKAFJQFKBASMU-QGZVFWFLSA-N |
| SMILES | B1(N2CCCC2C(O1)(C3=CC=CC=C3)C4=CC=CC=C4)C |
| Reference | <span style="font-size:12px;"><span style="color:#000000;"><span style="font-family:arial,helvetica,sans-serif;"><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">1. Parker, K.A. and Ledeboer, M.W. 1996. J. Org. Chem. 61: 3214-3217. PMID: 11667191</span><br style="box-sizing: border-box; color: rgb(51, 51, 51); font-family: openSans, arial, sans-serif; font-size: 14px; font-variant-ligatures: normal; orphans: 2; widows: 2;" /> |
