For research use only. Not for therapeutic Use.
While racemic 5-OH-DPAT (Axon 1006) is a potent and selective dopamine (DA) D2-receptor agonist, its R-enantiomer, (R)-5-OH DPAT is a weakly potent DA D2-receptor antagonist
| Catalog Number | I047445 |
| CAS Number | 182210-73-7 |
| Molecular Formula | C16H25NO.HBr |
| Purity | ≥95% |
| IUPAC Name | (6R)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol;hydrobromide |
| InChI | InChI=1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m1./s1 |
| SMILES | CCCN(CCC)[C@@H]1CCC2=C(C1)C=CC=C2O.Br |
| Reference | A Karlsson et al. (R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): Assessment of optical purities and dopaminergic activities. Chirality. 1989-1995, 2(2), 90-95.
S.L. Payne et al. Mechanisms of ligand binding and efficacy at the human D2(short) dopamine receptor. J. Neurochem. 2002, 82, 1106–1117. |
