(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose

• CAT Number: I041266
• CAS Number: 6612-91-5
• Molecular Formula: C15H18O6
• Molecular Weight: 294.30
• Purity: ≥95%
• Synonyms: [(3aR,5R,6R,6aR)-6-hydroxy-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methyl benzoate
• InChI: InChI=1S/C15H18O6/c1-15(2)20-12-11(16)10(19-14(12)21-15)8-18-13(17)9-6-4-3-5-7-9/h3-7,10-12,14,16H,8H2,1-2H3/t10-,11-,12-,14-/m1/s1
• InChIKey: WKRBIHIDJVMVGS-HKUMRIAESA-N
• SMILES: CC1(OC2C(C(OC2O1)COC(=O)C3=CC=CC=C3)O)C

(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Reference

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
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